Source: | Human Cells |
Description: | Recombinant Mouse Macrophage Colony-Stimulating Factor 1 is produced by our Mammalian expression system and the target gene encoding Lys33-Glu262 is expressed. |
Accession: | P07141 |
Known As: | Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm |
Predicted Mol Mass: | 26 Kda |
Apparent Mol Mass: | 37-80 KDa, reducing conditions |
Endotoxin: | < 0.01 EU/µg as determined by LAL test. |
Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution: | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Shipping: | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage: | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Background: | Macrophage colony-stimulating factor 1(M-csf)is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation,differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways,including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism,fertility and pregnancy. |
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