| Source: | Human Cells |
| Description: | Recombinant Mouse Thrombopoietin is produced by our Mammalian expression system and the target gene encoding Ser22Thr356 is expressed with a 6His tag at the N-terminus. |
| Accession: | P40226 |
| Known As: | Thrombopoietin; C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; Myeloproliferative leukemia virus oncogene ligand; THPO |
| Predicted Mol Mass: | 36.4 Kda |
| Apparent Mol Mass: | 65-105 KDa, reducing conditions |
| Endotoxin: | <0.05EU/μg as determined by LAL test. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, 2mM EDTA, pH 7.4. |
| Reconstitution: | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Shipping: | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage: | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Background: | Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets.Mature mouse Tpo shares 71% and 81% aa sequence homology with human and rat Tpo, respectively. It is an 80-85 kDa protein that consists of an N-terminal domain with homology to Erythropoietin (Epo) and a C-terminal domain that contains multiple N-linked and O-linked glycosylation sites. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
重组小鼠血小板生成素(TPO)
¥1,200.00
规格: 10μg
英文名字：Thrombopoietin (TPO),Mouse,Recombinant
质量标准：>95%,BR
| 规格 | 10μg |
|---|