Source: | Human Cells |
Description: | Recombinant Rat Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Gln155 is expressed with a 6His tag at the C-terminus. |
Accession: | P17108 |
Known As: | Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2 |
Predicted Mol Mass: | 16.3 Kda |
Apparent Mol Mass: | 14-16 KDa, reducing conditions |
Endotoxin: | < 1 EU/µg as determined by LAL test. |
Formulation: | Supplied as a 0.2 μm filtered solution of 5mM NaH2PO4, 5mM Citric acid, 150mM NaCl, pH 4.0. |
Shipping: | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Storage: | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Background: | Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. |
重组大鼠白介素2(IL-2)
¥620.00
规格: 10μg
英文名字:IL-2,Recombinant Rat Interleukin-2(C-6His)
质量标准:>95%,BR