重组大鼠白介素2(IL-2)

¥620.00

规格: 10μg

英文名字:IL-2,Recombinant Rat Interleukin-2(C-6His)
质量标准:>95%,BR
Source: Human Cells
Description: Recombinant Rat Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Gln155 is expressed with a 6His tag at the C-terminus.
Accession: P17108
Known As: Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2
Predicted Mol Mass: 16.3 Kda
Apparent Mol Mass: 14-16 KDa, reducing conditions
Endotoxin: < 1 EU/µg as determined by LAL test.
Formulation: Supplied as a 0.2 μm filtered solution of 5mM NaH2PO4, 5mM Citric acid, 150mM NaCl, pH 4.0.
Shipping: The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
Storage: Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Background: Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.  IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

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