| Source: | E.coli |
| Description: | Recombinant Human Interleukin-18 is produced by our E.coli expression system and the target gene encoding Tyr37-Asp193 is expressed. |
| Accession: | Q14116 |
| Known As: | Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MGC12320 |
| Predicted Mol Mass: | 18.2 Kda |
| Apparent Mol Mass: | 17 KDa, reducing conditions |
| Endotoxin: | <0.01EU/μg as determined by LAL test. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,5% Sucrose,0.1% Tween80,pH 7.4. |
| Reconstitution: | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Shipping: | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage: | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Background: | Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. |
重组人白介素18(IL-18)
¥1,110.00
规格: 10μg
英文名字：IL-18,Human;Recombinant Human Interleukin 18
质量标准：>95%,BR