| Source: | Human Cells |
| Description: | Recombinant Human/Mouse/Rat Growth Differentiation Factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed. |
| Accession: | O95390 |
| Known As: | Growth/differentiation factor 11; GDF-11; Bone morphogenetic protein 11; BMP-11 |
| Predicted Mol Mass: | 12.5 Kda |
| Apparent Mol Mass: | 13-20 KDa, reducing conditions |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Formulation: | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50% glycerol, pH 7.4. |
| Shipping: | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
| Storage: | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Background: | Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development. |
重组人骨形态发生蛋白11(BMP-11)
¥1,600.00
规格: 10μg
英文名字：Bone Morphogenetic Protein 11(BMP-11),Human,Recombinant
质量标准：>95%,BR