细胞松弛素E, Cytochalasin E
产品简介
细胞松弛素是可透过细胞的抑制肌动蛋白聚合的真菌代谢物。
分子式:C28H33NO7,分子量:495.56
物理性状及指标:
外观:……………………白色结晶粉末
熔点:……………………205~210°C
溶解性:…………………溶于DMSO(10mg/ml)、乙醇(2mg/ml)
炽灼残留:………………<0.1%
纯度:……………………>98%
生物活性:
The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin E is an epoxide-containing analog of cytochalasin B which potently and selectively inhibits the growth of endothelial cells (IC50 < 1 nM), impairing angiogenesis and tumor growth. This cytochalasin does not inhibit glucose transport or HIV-1 protease activity.
用途及描述:科研试剂
储存条件:
-15~-20°C