细胞松弛素H;Cytochalasin H
分子式:C30H39NO5, 分子量:493.6
物理性状及指标:
外观:……………………白色冻干粉
溶解性:…………………溶于DMSO、乙醇
炽灼残留:………………<0.1%
纯度:……………………>95%
生物活性:
The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin H is a potent inhibitor of actin incorporation into filaments. Like cytochalasin D, it also increases the steady-state diffusion coefficients of filaments, suggesting that it stimulates filament shortening. Cytochalasin H suppresses the production of reactive oxygen species by stimulated human neutrophils, blocks endocytosis of CD59 in lymphocytes, and shows anti-angiogenic activity bothin vitroandin vivo
用途及描述:科研试剂.
储存条件:-15~-20°C
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