盐酸四环素；Tetracycline hydrochloride
分子式：C22H24N2O8 .HCl分子量：480.90
简介：Tetracycline HCl是Tetracycline的盐酸盐，是一种广谱的聚酮类抗生素。本品为广谱抑菌剂，高浓度时具杀菌作用。用于治疗多种感染。
别名：四环素盐酸盐; 盐酸四环素； Tetracycline hydrochloride ；2-naphthacenecarboxamid
物理性状及指标：
外观：……………………黄色结晶性粉末
熔点：……………………220-223℃(lit.)
溶解性：…………………DMSO：96 mg/mL warmed (199.62 mM)；Water：30mg/mLwarmed；Ethanol：Insoluble
干燥失重：………………≤2.0%
含量：……………………Purity>98%,Potency≥900μg/mg
敏感性：…………………有引湿性；遇光色渐变深，在碱性溶液中易破坏失效。
IC50：……………………半数致死剂量(LD50)经口-大鼠- 6,443 mg/kg
储存条件：常温，避光防潮密闭干燥
生物活性
|
产品描述 |
Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negativebacteria. |
|
体外研究 |
Tetracyclines are broad-spectrum agents, exhibiting activity against a wide range of gram-positive and gram-negative bacteria, atypical organisms such as chlamydiae, mycoplasmas, and rickettsiae, and protozoan parasites. Tetracyclines inhibit bacterial protein synthesis by preventing the association of aminoacyl-tRNA with the bacterial ribosome. Tetracyclines traverse the outer membrane of gram-negative enteric bacteria through the OmpF and OmpC porin channels, as positively charged cation (probably magnesium)-tetracycline coordination complexes. |
|
体内研究 |
The tetracyclines have applications for the treatment of infections in poultry, cattle, sheep, and swine. In some cases, e.g., for therapeutic treatment of large numbers of poultry reared on commercial farms, the antibiotics are added directly to feed or water or can be administered in aerosols. Tetracyclines could be used as growth promotion or growth enhancement. Tetracyclines are used in aquaculture to control infections in salmon, catfish, and lobsters. |
用途及描述：科研试剂，广泛应用于分子生物学，药理学等科研方面，严禁用于人体。
【注意】
●我司产品为非无菌包装，若用于细胞培养，请提前做预处理，除去热原细菌，否则会导致染菌。
●部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，以上数据仅供参考交流研究之用。
我司所售出产品仅供于科研研究用途（非临床科研研究），每次销售产品行为都适用于我司网上所列明的通用销售条款。