肥胖抑制素(大鼠);Obestatin (mouse, rat)
分子式:C114H174N34O31 分子量:2516.81
氨基酸序列:Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2
产品形式:冻干粉。Lyophilized from 0.1% aqueous trifluoroacetate (TFA).
生物活性:
- Obestatin has been used to study its effect on serum glucose and enzymatic parameters in rats and used to investigate its effect on plasma acyl-ghrelin and body weight in wistar rat.
- Obestatin opposes the action of circulating appetite-inducing hormone-ghrelin and plays a vital role in weight regulation via hindering food intake, jejunal contraction and reducing the body weight. Obestatin mediates its activity by interacting with the G-protein coupled receptor 39 (GPR-39).
- Obestatin, an obesity peptide, along with Ghrelin peptides are derived from the same prepropeptide, Ghrelin. In contrast to Ghrelin, Obestatin suppresses food intake, body weight gain, and gastrointestinal motility in rodents.
溶解性:Water 0.5-1mg/mL
储存条件:
−20°C
运输条件:
2~8℃运输
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